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Each week I breakdown what the optimal lineups are for the main slate. I tend to run these Friday afternoon or Friday night to get the closest to final weekend projections and managing to get this some view time for you folks. Our optimizer constantly updates projections, so you may see some changes from what you find here. I highly encourage playing around with the optimizer, running models, changing projections, locking, excluding, and building various ways. These optimal lineups can be a base to your personal lineups, or to suggest what plays the optimizer is really keying in on. Below are Cash, GPP, and Stack lineups with brief thoughts on the potential success of the lineup. Premium users access all three, while non-premium will find just the cash lineup.

Russell Wilson comes in as the second highest projected QB this week, just a shade behind Tom Brady. The $700 difference looks to be enough of a savings to go him over Brady in actually all three lineups. Wilson is averaging 2.1 touchdowns per game over the last eight, and 0.40 fantasy points per snap. This is a great spot for Wilson to put up a solid game, as San Francisco ranks 29th against quarterbacks.

I found Carlos Hyde to be more of a tournament option this week, because the matchup is still pretty poor for Hyde. This is more of a volume play, hoping he can capitalize on that. Hyde is averaging 20.1 touches per game, and 1.08 fantasy points per touch. Tevin Coleman got a bump with Devonta Freeman ruled out for Sunday. Coleman should see 20 touches again this week, against a team that ranks 20th against running backs.

Larry Fitzgerald will dodge A.J. Bouye and Jaylen Ramsey this week, but this is still a tough spot against the number one pass defense in the league. Fitzgerald dropped down over $1,000 from last week, and is averaging 2.03 fantasy points per target. Fitz is averaging 9.8 targets per game. Michael Thomas is really propped up this week, and I am not sure why. His $7,200 is a little pricey for me, but is averaging 1.75 fantasy points per target. With Robert Woods out, Cooper Kupp is going to get a tick up in usage, and with New Orleans losing two corners, the Rams offense is a stackable one.

Jack Doyle is always a top PPR option when he is priced appropriately. Doyle is averaging 5.8 receptions per game, and 6.5 yards per target. Doyle is second in targets to Hilton, getting 24.5% of them. Joe Mixon is more of a game-script value than matchup, because Cleveland ranks 2nd in DVOA against the run. They haven't allowed a ton of fantasy production.

Jaguars defense is an easy pay up option this week, as Blaine Gabbert steps in against a good pass defense. Jags have one of the highest floors and ceilings this season.

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