| Date | Time | Game |
|---|---|---|
| Thursday, October 5 | 8:25 PM ET | New England Patriots @ Tampa Bay Buccaneers |
| Sunday, October 8 | 1:00 PM ET | Buffalo Bills @ Cincinnati Bengals |
| Sunday, October 8 | 1:00 PM ET | New York Jets @ Cleveland Browns |
| Sunday, October 8 | 1:00 PM ET | Carolina Panthers @ Detroit Lions |
| Sunday, October 8 | 1:00 PM ET | San Francisco 49ers @ Indianapolis Colts |
| Sunday, October 8 | 1:00 PM ET | Tennessee Titans @ Miami Dolphins |
| Sunday, October 8 | 1:00 PM ET | Los Angeles Chargers @ New York Giants |
| Sunday, October 8 | 1:00 PM ET | Arizona Cardinals @ Philadelphia Eagles |
| Sunday, October 8 | 1:00 PM ET | Jacksonville Jaguars @ Pittsburgh Steelers |
| Sunday, October 8 | 4:05 PM ET | Seattle Seahawks @ Los Angeles Rams |
| Sunday, October 8 | 4:05 PM ET | Baltimore Ravens @ Oakland Raiders |
| Sunday, October 8 | 4:25 PM ET | Green Bay Packers @ Dallas Cowboys |
| Sunday, October 8 | 8:30 PM ET | Kansas City Chiefs @ Houston Texans |
| Monday, October 9 | 8:30 PM ET | Minnesota Vikings @ Chicago Bears |
Week 5 Fantasy Analysis
Aaron Rodgers gets to take on this Dallas secondary again, in which he destroyed in the playoffs. The loss of Brandon Carr might be big for this team this year, and not much has been done to fill it in over the offseason. Vintage Rodgers game is incoming for fantasy purposes. The Colts get a cupcake matchup against San Francisco at home. Andrew Luck and company are all top plays against this bottom ten defense at home.