| Date | Time | Game |
|---|---|---|
| Thursday, September 7 | 8:30 PM ET | Kansas City Chiefs @ New England Patriots |
| Sunday, September 10 | 1:00 PM ET | New York Jets @ Buffalo Bills |
| Sunday, September 10 | 1:00 PM ET | Atlanta Falcons @ Chicago Bears |
| Sunday, September 10 | 1:00 PM ET | Baltimore Ravens @ Cincinnati Bengals |
| Sunday, September 10 | 1:00 PM ET | Pittsburgh Steelers @ Cleveland Browns |
| Sunday, September 10 | 1:00 PM ET | Arizona Cardinals @ Detroit Lions |
| Sunday, September 10 | 1:00 PM ET | Jacksonville Jaguars @ Houston Texans |
| Sunday, September 10 | 1:00 PM ET | Tampa Bay Buccaneers @ Miami Dolphins |
| Sunday, September 10 | 1:00 PM ET | Oakland Raiders @ Tennessee Titans |
| Sunday, September 10 | 1:00 PM ET | Philadelphia Eagles @ Washington Redskins |
| Sunday, September 10 | 4:05 PM ET | Indianapolis Colts @ Los Angeles Rams |
| Sunday, September 10 | 4:25 PM ET | Seattle Seahawks @ Green Bay Packers |
| Sunday, September 10 | 4:25 PM ET | Carolina Panthers @ San Francisco 49ers |
| Sunday, September 10 | 8:30 PM ET | New York Giants @ Dallas Cowboys |
| Monday, September 11 | 7:10 PM ET | New Orleans Saints @ Minnesota Vikings |
| Monday, September 11 | 10:20 PM ET | Los Angeles Chargers @ Denver Broncos |
Week 1 Fantasy Analysis
Week 1 offers up some friendly quarterback matchups, but also some bad ones. Detroit allowed the fourth most fantasy points per game to opposing quarterbacks last season, putting Carson Palmer in a good spot to start strong. Tennessee and Oakland allowed the sixth and seventh most fantasy points per game to quarterbacks. Hello Marcus Mariota and Derek Carr. Drew Brees and Aaron Rodgers are on the other end of the spectrum having tough matchups. Minnesota and Seattle both were top ten in fantasy points allowed this season.